spleen; [1298]"or in the nails; if it appear black, it signifieth much care, grief, contention, and melancholy;” the reason he refers to the humours, and gives instance in himself, that for seven years space he had such black spots in his nails, and all that while was in perpetual lawsuits, controversies for his inheritance, fear, loss of honour, banishment, grief, care, &c. and when his miseries ended, the black spots vanished.  Cardan, in his book de libris propriis, tells such a story of his own person, that a little before his son’s death, he had a black spot, which appeared in one of his nails; and dilated itself as he came nearer to his end.  But I am over tedious in these toys, which howsoever, in some men’s too severe censures, they may be held absurd and ridiculous, I am the bolder to insert, as not borrowed from circumforanean rogues and gipsies, but out of the writings of worthy philosophers and physicians, yet living some of them, and religious professors in famous universities, who are able to patronise that which they have said, and vindicate themselves from all cavillers and ignorant persons.

SUBSECT.  V.—­Old age a cause.

Secondary peculiar causes efficient, so called in respect of the other precedent, are either congenitae, internae, innatae, as they term them, inward, innate, inbred; or else outward and adventitious, which happen to us after we are born:  congenite or born with us, are either natural, as old age, or praeter naturam (as [1299]Fernelius calls it) that distemperature, which we have from our parent’s seed, it being an hereditary disease.  The first of these, which is natural to all, and which no man living can avoid, is [1300]old age, which being cold and dry, and of the same quality as melancholy is, must needs cause it, by diminution of spirits and substance, and increasing of adust humours; therefore [1301] Melancthon avers out of Aristotle, as an undoubted truth, Senes plerunque delirasse in senecta, that old men familiarly dote, ob atram bilem, for black choler, which is then superabundant in them:  and Rhasis, that Arabian physician, in his Cont. lib. 1. cap. 9, calls it [1302]"a necessary and inseparable accident,” to all old and decrepit persons.  After seventy years (as the Psalmist saith) [1303]"all is trouble and sorrow;” and common experience confirms the truth of it in weak and old persons, especially such as have lived in action all their lives, had great employment, much business, much command, and many servants to oversee, and leave off ex abrupto; as [1304]Charles the Fifth did to King Philip, resign up all on a sudden; they are overcome with melancholy in an instant:  or if they do continue in such courses, they dote at last, (senex bis puer,) and are not able to manage their estates through common infirmities incident in their age; full of ache, sorrow and grief, children again, dizzards, they carl many times as they sit, and talk to themselves, they are