A student of his make-up, and acquainted with present developments concerning the internal secretions, given an opportunity to observe him as we have when he was alive, and at the height of his success, would have had every reason for classing him a pituitary-centered, ante-pituitary superior, post-pituitary inferior, with an instability of both that would lead to his final degeneration. Besides, his insatiable energy indicated an excellent thyroid, his pugnacity, animality and genius for practical affairs a superb adrenal. Given the kind of pituitary he possessed, with its great intellectual potential energy and the relation between the two parts which would further the objects of an intellectual machine, plus a remarkable thyroid and adrenal, plus the military education Napoleon had, and the character of the Revolution into which he was plunged, and we have the conditions out of which his career emerged as inevitable.
That it was his pituitary which first failed him, rather than the thyroid or adrenal, which might have, is demonstrated by a number of considerations. Before he made himself Emperor, it was noticed that he was becoming fat, a pituitary symptom. A comparison of portraits at different stages of his rise and fall shows an increasing abdominal paunch, and a laying down of fat in the pituitary areas, around the hips, the legs and so on. The beginning of weakness in judgment that he was to exhibit soon in the invasion of Russia manifested itself at the same time. His keen calculating ability attained the peak of its curve at Austerlitz, Jena and Friedland. Thereafter, the descent begins. A rash, grandiose, speculative quality enters his projects, and divorces the elaborate coordination of means and end from his plans. That his thyroid energy capacity did not fail him is indicated by the fact that at St. Albans he would ride for three hours at the end of the day to tire himself sufficiently for sleep. That his adrenals were not affected is indicated by the brutality which remained characteristic to the end of his life.