The Canadian medical scientist Charles Herbert Best (1899-1978) codiscovered insulin in 1921. He also discovered the enzyme histaminase, and his studies on choline established its importance as a dietary factor.

Charles H. Best was born on February 27, 1899, at West Pembroke, Maine. His parents, Dr. Herbert Huestes Best and Luella Fisher Best, were Canadian. Charles entered the University of Toronto in 1916, but interrupted his studies to join the Canadian army. After World War I he resumed his studies at the University of Toronto and graduated in May 1921.

Discovery of Insulin

The day after his examinations Best began work with Frederick Banting in the department of physiology. Best had been asked to assist in the chemical procedures involved in the research. He and Banting started their work on the extraction of pancreatic tissue and the treatment of depancreatized dogs. This project led to the discovery of insulin later that summer.

Best...