Everything you need to understand or teach Lord of the Two Lands by Judith Tarr.
While the above features may seem to modernize the story, its strongest theme is the ancient one of destiny.
Alexander's mother was said to have given him his unique sense of destiny; she told him he was the son of a god.
In this novel the tale goes back even further. Nectanebo, the last native Egyptian pharaoh (and Meriamon's father) is shown in the prologue. He is scrying the scene of Alexander's conception...