Jonas Salk was one of the United States's best-known microbiologists, chiefly celebrated for his discovery of his polio vaccine. Salk's greatest contribution to immunology was the insight that a "killed virus" is capable of serving as an antigen, prompting the body's immune system to produce antibodies that will attack invading organisms. This realization enabled Salk to develop a polio vaccine composed of killed polio viruses, producing the necessary antibodies to help the body to ward off the disease without itself inducing polio.

The eldest son of Orthodox Jewish-Polish immigrants, Jonas Edward Salk was born in East Harlem, New York, on October 28, 1914. His father, Daniel B. Salk, was a garment worker, who designed lace collars and cuffs and enjoyed sketching in his spare time. He and his wife, Dora Press, encouraged their son's academic talents, sending him to Townsend Harris High School for the gifted. There, young Salk was...